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HomeResearch ProjectsUtilizing temporal and biogeographical comparative functional genomics to inform screening for novel antimicrobial targets

Utilizing temporal and biogeographical comparative functional genomics to inform screening for novel antimicrobial targets

Project Summary

Our lab utilizes comparative functional genomics to quantify distributions of antibiotic-resistance genes in microbial pathogens. Gene distribution patterns illustrate how pathogenic adaptations move through bacterial populations. This information is being integrated into algorithms used to simulate patterns of gene distribution among and between populations.

Relevance

Successful efforts to meet the challenge of antibiotic resistance can be bolstered by understanding strategies that microbes are using to acquire resistance. Genomic analysis is informing the search for novel molecular targets that could provide a means toward new antimicrobial therapy.

Larry Feinstein at UMPI

Investigator

Larry Feinstein, Ph.D.
University of Maine at Presque Isle
Assistant Professor of Biology
ude.eniamnull@nietsnief.yrral

Maine INBRE is funded by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health.

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